Pain-seq is a group of resources containing multi-omic data that we and our collaborators have published on our journey to improve our the understanding of and treatments for chronic pain and headache disorders
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Cell atlases for the dorsal root ganglion (DRG) and trigeminal ganglion (TG) across six species and 31 datasets including humans, non-human primates and rodents. This resource also includes a cell type nomenclature conversion tool to compare neuronal nomenclatures across multiple studies.
An atlas of immune cells in three distinct inflammatory pain conditions and a database of their receptor-ligand neuroimmune interactions.
A cell atlas of human and mouse trigeminal ganglia that describes conserved and species-specific gene expression patterns and implicates multiple cell types in migraine pathophysiology.
A resource describing the transcriptional responses of distinct peripheral sensory neuron subtypes in animal models of pain (e.g. injury, inflammatory, chemotherapy-induced neuropathy) at single-nuclei resolution.